Glossary entry (derived from question below)
English term or phrase:
\'driver\' gene
Serbian translation:
„driver“/pokretački gen
Added to glossary by
Svetomir Mijovic
Apr 11, 2023 20:33
1 yr ago
14 viewers *
English term
Serbia
Experienced Sci/Tech translator
Native in: Serbian 
, Serbo-Croat (Variant: Serbian)
Works in: Serbo-Croat to English, English to Bosnian, English to Croatian, and 1 more.
'driver' gene
English to Serbian
Medical
Medical: Pharmaceuticals
antibody construct
Several key players involved in disease pathogenesis have been identified and can be interrogated as actionable targets. One such activating "driver" gene that is most commonly mutated in approximately 30% of AML is FLT3.
Proposed translations
(Serbian)
| 3 | „driver“/pokretački gen |
Nebojša Mihaljević
|
| 4 | Критичан ген (за тумор) |
Slobodan Kozarčić
|
Proposed translations
13 hrs
Nebojša Mihaljević
Montenegro
Montenegro
Native in Serbian
Montenegro
Translator & Electronic Engineer
Native in: Serbian (Variant: Montenegrin ) 
, Montenegrin
Works in: English to Serbian, English to Montenegrin, English to Serbo-Croat, and 6 more.
Related KudoZ points
:
52
Selected
„driver“/pokretački gen
Reference:
1. FLT3 je gen koji sadrži kôd za nastanak proteina pod nazivom receptor tirozin-kinaza (RTK), https://www.genecards.org/cgi-bin/carddisp.pl?gene=FLT3, https://sr.wikipedia.org/wiki/Receptor_tirozinska_kinaza
2. Disregulacija aktivnosti RTK uključena je u progresiju brojnih leukemija i drugih maligniteta [15]. Najčešće su u pitanju hromozomalne translokacije koje utiču na regulaciju tirozin-kinazne aktivnosti c-kit receptora, Flt3 receptora i PDGFβ/fibroblast growth factor receptor (FGF1) receptora, što je pokazano kod sistemske mastocitoze, akutne mijeloidne leukemije (AML) ili hronične granulocitne leukemije (HGL) [35], https://scindeks-clanci.ceon.rs/data/pdf/0025-8105/2010/0025...
1. FLT3 je gen koji sadrži kôd za nastanak proteina pod nazivom receptor tirozin-kinaza (RTK), https://www.genecards.org/cgi-bin/carddisp.pl?gene=FLT3, https://sr.wikipedia.org/wiki/Receptor_tirozinska_kinaza
2. Disregulacija aktivnosti RTK uključena je u progresiju brojnih leukemija i drugih maligniteta [15]. Najčešće su u pitanju hromozomalne translokacije koje utiču na regulaciju tirozin-kinazne aktivnosti c-kit receptora, Flt3 receptora i PDGFβ/fibroblast growth factor receptor (FGF1) receptora, što je pokazano kod sistemske mastocitoze, akutne mijeloidne leukemije (AML) ili hronične granulocitne leukemije (HGL) [35], https://scindeks-clanci.ceon.rs/data/pdf/0025-8105/2010/0025...
4 KudoZ points awarded for this answer.
Comment: "Hvala!"
1 day 1 hr
Slobodan Kozarčić
Serbia
Serbia
Native in Serbian
Serbia
900 films/500 medical rep/two books/tech
Native in: Serbian (Variant: Montenegrin ) , Bosnian
Works in: English to Serbian, English to Bosnian, Serbian to English, and 4 more.
Related KudoZ points
:
32
Критичан ген (за тумор)
https://www.nature.com/articles/srep38988#:~:text=Genes in w...
https://lundberginstitute.org/driver-and-passenger-mutations...
https://repozitorij.unizg.hr/islandora/object/pmf:5774/datas...
Гени чија промена доводи до настанка тумора називају се гени критични за тумор.
https://lundberginstitute.org/driver-and-passenger-mutations...
https://repozitorij.unizg.hr/islandora/object/pmf:5774/datas...
Гени чија промена доводи до настанка тумора називају се гени критични за тумор.
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