As-Treated population

Russian translation: популяция (совокупность пациентов) согласно фактически полученному лечению

GLOSSARY ENTRY (DERIVED FROM QUESTION BELOW)
English term or phrase:As-Treated population
Russian translation:популяция (совокупность пациентов) согласно фактически полученному лечению
Entered by: Elena Doroshenko

07:55 May 26, 2017
English to Russian translations [PRO]
Medical - Medical: Pharmaceuticals
English term or phrase: As-Treated population
Intent-to-Treat population included all patients who were randomized, with study drug assignment designated according to initial randomization, regardless of whether patients received study drug or received a differentdrug from that to which they were randomized.

As-Treated population included all patients who received at least 1 dose of study drug with treatment assignments designated according to actual study treatment received.

The median duration of study treatment in the sunitinib and placebo arms was 12.4 months, each (see Section 14.4, Table 14.4.1.2).
Maxim Polukhin
Local time: 19:58
популяция (совокупность пациентов) согласно фактически полученному лечению
Explanation:
популяция (совокупность пациентов) согласно фактически полученному лечению http://www.multitran.ru/c/m.exe?l1=1&l2=2&s=As-Treated popul...

The formal definition of the "Intention to Treat" is usually referred to the one suggested by Fisher, LD et al. in “Intention to treat in clinical trials in Statistical Issues in Drug Research and Development. Edited by Peace KE (1990)”. Intention to Treat population “Includes all randomized patients in the groups to which they were randomly assigned, regardless of their adherence with the entry criteria, regardless of the treatment they actually received, and regardless of subsequent withdrawal from treatment or deviation from the protocol”.

In other words, ITT analysis includes every subject who is randomized according to randomized treatment assignment. It ignores noncompliance, protocol deviations, withdrawal, and anything that happens after randomization. ITT analysis is usually described as “once randomized, always analyzed”. ITT analysis is referred as ‘as randomized’ - the opposite of the term ‘as treated’.

In majority of cases, if all randomized subjects receive their allocated treatments and if there is no randomization error, the ‘as treated’ analysis will be the same as 'as randomized' analysis.

If some randomized subjects do not receive the randomly alloccated treatment and if there are randomization errors, ‘as treated’ population will be different from ITT population or 'as randomized' population. http://onbiostatistics.blogspot.ru/2013/09/as-treated-versus...
Selected response from:

Elena Doroshenko
Russian Federation
Grading comment
Спасибо!
4 KudoZ points were awarded for this answer



Summary of answers provided
4 +3популяция (совокупность пациентов) согласно фактически полученному лечению
Elena Doroshenko


  

Answers


14 mins   confidence: Answerer confidence 4/5Answerer confidence 4/5 peer agreement (net): +3
as-treated population
популяция (совокупность пациентов) согласно фактически полученному лечению


Explanation:
популяция (совокупность пациентов) согласно фактически полученному лечению http://www.multitran.ru/c/m.exe?l1=1&l2=2&s=As-Treated popul...

The formal definition of the "Intention to Treat" is usually referred to the one suggested by Fisher, LD et al. in “Intention to treat in clinical trials in Statistical Issues in Drug Research and Development. Edited by Peace KE (1990)”. Intention to Treat population “Includes all randomized patients in the groups to which they were randomly assigned, regardless of their adherence with the entry criteria, regardless of the treatment they actually received, and regardless of subsequent withdrawal from treatment or deviation from the protocol”.

In other words, ITT analysis includes every subject who is randomized according to randomized treatment assignment. It ignores noncompliance, protocol deviations, withdrawal, and anything that happens after randomization. ITT analysis is usually described as “once randomized, always analyzed”. ITT analysis is referred as ‘as randomized’ - the opposite of the term ‘as treated’.

In majority of cases, if all randomized subjects receive their allocated treatments and if there is no randomization error, the ‘as treated’ analysis will be the same as 'as randomized' analysis.

If some randomized subjects do not receive the randomly alloccated treatment and if there are randomization errors, ‘as treated’ population will be different from ITT population or 'as randomized' population. http://onbiostatistics.blogspot.ru/2013/09/as-treated-versus...

Elena Doroshenko
Russian Federation
Specializes in field
Native speaker of: Russian
PRO pts in category: 139
Grading comment
Спасибо!

Peer comments on this answer (and responses from the answerer)
agree  Tatiana Nikitina
23 mins
  -> Спасибо, Татьяна!

agree  673286 (X): получившие лечение как есть
2 days 9 hrs
  -> Спасибо!

agree  Alla_K
882 days
  -> Спасибо!
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